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The Application of Immersion Specimen in Teaching

2025 / 07 / 01

Immersion specimens have various applications in teaching:1、 Visual display of biological morphology and structurePlant teaching: In botany teaching, soaking specimens can effectively showcase the organs of plants. For example, when displaying immersed specimens of flowers, students can clearly see the number, shape, and color of petals, as well as the structure of stamens (including stamens and pistils). Soak specimens like lilies allow students to observe that they have 6 petals, 6 stamens, and 1 pistil, and can be stored for a long time, making it convenient for students to observe at any time without being limited by the flowering period. For the fruits and seeds of plants, soaking specimens can also display their external morphology and internal structure. For example, by soaking pea pod specimens, students can see the arrangement of pea seeds in the pods.Animal teaching: In animal science teaching, specimen immersion allows students to intuitively understand the appearance of animals. Taking fish as an example, immersion specimens can display the fish's body size, types of fins (dorsal fin, pectoral fin, pelvic fin, anal fin, and caudal fin), and their positions. Students can observe the morphological differences of fins in different fish species, such as the elongated dorsal fin of crucian carp and the wider dorsal fin of fighting fish. For some small invertebrates, such as earthworm specimens, their link structures can be clearly presented, helping students understand the characteristics of link animals.2、 Assist in explaining knowledge of biological classificationClassification display: Immersion specimens can serve as physical display materials for biological classification. For example, when explaining the classification of vertebrates, display immersion specimens from different classes (such as fish, amphibians, reptiles, birds, and mammals). By comparing the immersion specimens of fish (with gill respiration and fins) and amphibians (with gill respiration for juveniles, lung respiration and skin assisted respiration for adults, and limbs), students can more intuitively understand the main differences between different classes and master the basic knowledge of biological classification.Species diversity presentation: Teachers can use immersion specimens to display species diversity within a specific group. For example, when explaining the insect class, display immersion specimens of various insects such as locusts, butterflies, bees, etc. Students can observe differences in wing morphology (locusts have leathery forewings and membranous hindwings, butterflies have colorful and membranous wings) and mouthparts types (locusts have chewing mouthparts, butterflies have siphon mouthparts), and appreciate the richness and diversity of insect species.3、Help understand the ecological relationships of organismsFood chain display: A simple food chain model can be constructed for teaching through a series of immersion specimens. For example, by displaying immersion specimens of plankton, small fish, and large fish, teachers can explain the relationship between plankton as primary producers being preyed upon by small fish and small fish being preyed upon by large fish, allowing students to better understand the energy flow in the food chain and ecosystem.Biological habitat environment correlation: Immersion specimens can also be combined with an introduction to the biological habitat environment. For example, when displaying immersion specimens related to mangrove ecosystems, immersion specimens such as mangrove plants (such as okra), fiddler crabs, and mudskippers living in mangroves are also displayed, accompanied by pictures or videos of the muddy intertidal environment of mangroves, allowing students to understand the interrelationships between these organisms and their environment.

Paraffin tissue section preservation

2024 / 06 / 06

Many laboratory researchers are accustomed to storing tissue wax blocks for a long time at room temperature after sectioning, and the tissue after sectioning is prone to antigen loss for long-term storage at room temperature.  Some studies have found that when sections are stored at room temperature for more than 3 months, immunohistochemical staining results are weakened or even negative. Therefore, some scholars have carried out new and old slice preservation time control experiments. 11 different tissue wax blocks were selected and 10 pieces were cut continuously for a total of 110 pieces per case, and placed in room temperature air for 1 month, 3 months, 6 months, and 1 year, and then the control experiment was carried out with new sections. The experimental results showed that when stored at room temperature for 3 months after wax sectioning, the sensitivity of antigens to most antibodies decreased by 50%, and the antigen loss of some sections was more. Most antibodies did not show positive results after 6 months of sectional storage, and only a few sections had weak positive expression after storage for more than 1 year, especially nuclear expression antigen loss was more prominent.  The reason may be related to oxidation, so in practical work, wax sealing sections and -20 degrees cryopreservation tissue sections can be used to avoid antigen loss, or paraffin tissue blocks can be stored at 4 degrees, and then sectioned when used, which can greatly reduce the antigen loss rate.

The Collision of Science and Childlike Innocence The Brilliant Blossoming of Juvenile Dreams

2025 / 09 / 24

September 2025 marks the first National Science Popularization Month. On the morning of September 20, the Weike Science and Education Life Science Popularization Base, under the organization of the Xinxiang Municipal Bureau of Science and Technology, jointly held the 2025 Xinxiang High-Tech Zone Science Popularization Promotion Activity at Daqiao Yueshidai (Bridge Joy Times) together with science and technology-oriented off-campus training institutions and technology-based enterprises. The diverse on-site forms of presenting science and technology created a series of science popularization feasts for citizens and young people. The Weike Science and Education Life Science Popularization Base brought a wealth of life science exhibits to students, among which children's microscopes attracted the students' attention. Under the guidance of volunteers, the children operated the microscopes by themselves: placing specimens on the stage, adjusting the light source, turning the coarse focusing knob... After a series of operations, the children observed the cell structure of onion epidermis and the butterfly wings under the microscope. "So this is what onion skin cells look like!" "Great! I finally got to see it!" The children exclaimed in amazement, their faces beaming with joy. By operating the microscopes in person, the children experienced the wonder of the microscopic world and significantly improved their observation and hands-on skills. Subsequently, the fascinating animal and plant specimens as well as human tissue and organ models aroused great interest among the students. Life science volunteers gave in-depth yet easy-to-understand science popularization explanations to the children, which not only broadened their horizons but also stimulated their strong interest in life science. Through the close-up experience of the diversity and adaptability of organisms, the seeds of protecting the ecological environment, building a beautiful homeland, and achieving harmonious coexistence between humans and nature were subtly planted in the children's hearts.By guiding the children to have an immersive experience, this activity allowed them to feel the charm and power of life science up close, sowed the seeds of loving science and learning science well in their hearts, and enhanced their scientific literacy.

Promote the spirit of science and popularize scientific knowledge

2025 / 09 / 10

On the afternoon of September 4th, the launch ceremony of the 2025 Xinxiang National Science Popularization Month, jointly organized by the Xinxiang Association for Science and Technology, Xinxiang Science and Technology Bureau, Xinxiang Education Bureau, and Xinxiang Municipal Committee of the Communist Youth League, was successfully held at the Xinxiang Youth Activity Center. The Weike Science and Education Life Science Popularization Education Base was invited to participate in the launch ceremony and conduct interactive science popularization exhibitions.At the launch ceremony, we learned about the deeds of Zhang Qinglian, the most beautiful technology worker in Henan Province. The atmosphere was lively, the content was exciting, and the forms were diverse. VIC Science and Education Life Science Popularization Volunteers were fortunate to have the opportunity to showcase cutting-edge technological achievements and their applications in daily life with enterprises and institutions in the fields of cutting-edge technology, smart agriculture, traditional Chinese medicine health, aerospace, and other industries in our city.At the event, our volunteers enthusiastically explained the parts and functions of human tissues and organs to representatives of primary and secondary school teachers and students, as well as science enthusiasts from all walks of life. The lively and interesting science popularization and immersive interactive experience made life science knowledge no longer boring.Integrating education with entertainment and learning with fun. Our volunteers help teenagers understand the mysteries of life sciences in a joyful atmosphere. This unique science popularization activity not only enriches the spiritual and cultural life of young people, but also improves their psychological literacy.Through this event, we will actively undertake the core functions of disseminating scientific knowledge, enhancing the scientific literacy of the entire population, and promoting technological innovation, injecting strong impetus into improving the scientific literacy of the people in Xinxiang and empowering its innovative development.

The production process of frozen sections

2024 / 06 / 06

Frozen sectioning method is the most commonly used sectioning technique in histochemistry, especially enzyme histochemistry, fixed or unfixed tissue samples can be frozen section, fresh tissue frozen sections for tissue intracellular enzyme preservation is also a commonly used sectioning method in immunocytochemical research, can better preserve a variety of antigens, especially the antigenicity of surface antigens.  1. PreparationClean up the test bench and instrumentsTurn on the cryomicrotome and pre-reduce the cryomicrotome to the required temperature (-15~-20 °C)Prepare the processed slides, blades, glue and medicines  2. Clamp the frozen tissue block on the microtome holder, start the rough advance and withdrawal button, turn the knob, and smooth the tissue. 3. Adjust the thickness to be cut, according to different tissues, in principle, it is a cell-intensive thin cut, and the fiber multicellular thin can be slightly thick cut, generally between 5 ~ 10μm. 4. Adjust the anti-coil plate. The key to making frozen slices lies in the adjustment of the anti-roll plate, which requires the operator to be careful and accurately adjust it well and adjust it to the appropriate position. When slicing, cut out a complete, smooth slice. When the cut tissue adheres to a clean slide, gently apply a gentle force in one direction to avoid wrinkles during the tissue spreading process, ensure the integrity of the tissue structure and the beauty of the section.
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